SYN1 antibody

Catalog No. ABIN5540676

The Rabbit Polyclonal anti-SYN1 antibody has been validated for WB, IF, ICC and IP. It is suitable to detect SYN1 in samples from Human, Rat, Mouse and Cow.

Quick Overview for SYN1 antibody (ABIN5540676)

Target: SYN1 (Synapsin I (SYN1))

Reactivity: Human, Rat, Mouse, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Product Details anti-SYN1 Antibody

Specificity: Specific for the ~78k synapsin I doublet in Western blots of rat brain extracts. Immunolabeling blocked by preadsorption of antibody with the protein used to generate the antibody.

Purification: Affinity purification using a column to which the native protein was coupled

Immunogen: Native protein purified from bovine brain

Isotype: Ig Fraction

Application Details

Application Notes: Western blot: 1/1000. Immunohistochemistry / immunoflourescence: 1:1000. Immunoprecipitation: 2 μL per 200 μg lysate.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 100 μL in 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg BSA per ml and 50 % glycerol

Storage: 4 °C,-20 °C

Storage Comment: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for SYN1

Target: SYN1 (Synapsin I (SYN1))

Alternative Name: synapsin-1

Background: Synapsin I plays a key role in synaptic plasticity in brain (Feng et al., 2002 Nayak et al., 1996). This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. In addition to its role in plasticity, the expression of synapsin I is a precise indicator of synapse formation (Moore and Bernstein, 1989 Stone et al., 1994). Thus, synapsin I immunocytochemistry provides a valuable tool for the study of synaptogenesis. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation (Jovanovic et al., 2001 Kao et al., 2002).

UniProt: P17599